Salmeterol
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Q: What’s inside salmeterol in prescription Advair which could kill a few asthmatics?
Salmeterol, like formederol, falls under the class of anti-asthma drugs called LABAs…or long-acting beta agonists. But in very few asthmatics, a few who took prescription Advair, which contains salmeterol, died from asthma still. Why is this happening even though Advair was approved by the FDA as an controller medicine for all asthmatics? And what can we do about it?
A: What an insightful question.
While salmeterol has reduced medical withdrawals due to asthma control compared with SABA’s, it has also been associated with a higher risk for death among patients with severe asthma.
In the most current study of salmeterol vs placebo, salmeterol was associated with slightly higher rates of asthma-related death, respiratory-related death, and the combination of asthma-related deaths, intubation, or mechanical ventilation. This difference largely was confined to African American patients.
Whether this risk is due to factors including but not limited to a physiologic treatment effect, genetic factors, or patient behaviors leading to poor outcomes remains unknown and that is where we are at with this drug.
I guess one would think that the only thing that can be done is a concerted effort to have it withdrawn. But, there is a huge popiulation that this drug is very effective with. So maybe there needs to be a strong re-evaluation to which patient poplation to prescribe the drug to.
Q: Is anyone on Salmeterol xinafoate? for asthma?
What is meant to do? and how have you found it? any side effects? and whats your dosage?
A: Hi Gemma,
Salmeterol is a long-acting beta2-adrenergic receptor agonist drug , which is basically like the ventolin, blue inhaler, but longer lasting.
These are usually taken as prescribed by your doctor, should be accompanying a steroid inhaler.
I was on this inhaler, along with Qvar steroid inhaler and I was taking the salmeterol 2x puff, twice daily. I found the salmeterol inhaler helped, but I got terrible shakes and I found I could not sleep at night, because I felt so on edge. They consequently reduced the dose and then eventually I was removed entirely from this drug and I am now taking Symbicort 200/6, which is basically a long lasting inhaler and a steroid inhaler in one.
I have found that with asthma medications, what might work for one person, might not work for another and some might never experience any side effects, where others might. Just see how it goes, if you’re not happy go back to your GP. There are other asthma inhalers out there.
Good luck -x-
Q: what is the best way to cure asthma?want to know other alternative herbal med for my kids asthma.?
my kid is 4yrs old and every month, he will be given antibiotics because he has colds eventually leads to cough and asthma. he has maintenance med, (salmeterol+fluticasone propionate, cetirizine) still he cough. I give him also nebulization (combivent). how can he be asthma free? are there herbal med? or natural asthma prevention? my kid is obese. at 4yrs old he is 29kg. and i find it hard to let him on diet because he cant understand what diet is.how can i let him reduce his weight?
A: don’t mess with asthma! Trying a bunch of natural nonsense drugs may get him into a life and death situation. Look at your house, see what is causing his problems, smoking, paint fumes, animal dander, dust etc. eliminate it from your environment and pray for him to outgrow it. a number of kids do. As for the weight, you caused it by overfeeding him, you have to take steps to help him eat healthy foods. Keep him away from jusk food, no soda, no cookies , no crackers….teach him to eat good food and he will lost the weight.
Q: Salmeterol(serevent) Possible overdose? ……Please advise?
Hi I had an asthma attack this morning and forgot my blue inhaler and only had serevent with me I used that, at least 20 puffs at 25mcg each a total of 500 mcg. I didn’t realize that it would not help an attack ,fortunately my friend was there and he ran and got his. I am now ok but I am shaking , almost tingling all over and have a sore head. Please advise. Thanks to all who answer
A: Yes, call the poison control center in your area. If not that then go to the ER. Salmeterol overdose can cause rapid heart rate, hypertension, agitation, etc….
They may need to monitor your vital signs for the next few hours, and administer beta blockers in a controlled setting if necessary. Also, make sure you understand which inhalers are for rescue and which are for maintenance. Maintenance inhalers aren’t useful for acute attacks and only lead to overdose as a patient keeps trying to get them to work quickly.
Salmeterol is long-acting by design so the effect are going to be there for a number of hours. So, don’t ignore it.
Q: Anyone on salmeterol (SEREVENT) had side effects from it?
I should add my son had heart palpitations after starting that medication, his dr. says it’s a very rare reaction, I’m trying to figure out how rare it is, really.
A: It is a long acting B agonist. The blue inhaler ventolin is for more immediate treatment of symptoms. The salmeterol works over a longer time. The side effects are the same as ventolin….fine tremor, mild anxiety, fast heart rate. The dose of drug is very small because it is inhaled. These side effects are negligable compared to the panic and tight chest of an asthma attack.
Q: seretide……. Salmeterol xinafoate?
what is the classification of the drug Seretide?
A: Salmeterol (Serevent) is a long-acting Beta2-specific bronchodilator. Flovent (Fluticasone) is an inhaled steroid. Seretide is a combination inhaled steroid/long-acting bronchodilator.
Q: Which of the following drugs is classified as a topical steriod?
Albuterol (ventolin, Proventil)
Salmeterol (Serevent)
Fluocinolone (Synalar)
Prednisone (Deltasone)
A: Marie,
These details could have been researched personally using your library or the internet. I presume that this method involves less work for you. Your answer should be Fluocinolone (Synalar) which is a topical steroid. Prednisone (Deltasone) is a Corticosteroid, which is a medication that is chemically similar to natural steroids and duplicates their actions. Salmeterol (Serevent) is a long-acting beta2-adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Albuterol (ventolin, Proventil) is a bronchodilator used for asthma and emphysema and other lung conditions.
ALL ANSWERS SHOULD BE THOROUGHLY RESEARCHED, IN ANY FORUM AND ESPECIALLY IN THIS ONE. – MANY ANSWERS ARE FLAWED.
It is extremely important to obtain an accurate diagnosis before trying to find a cure. Many diseases and conditions share common symptoms.
The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.
Hope this helps
matador 89
Q: For People Who Are On ADVAIR DISKUS?
Hi,
(1.) Have u been on any other prevetive asthma attack medince before u went on Advair???
(2.) If so what???
(3.) And did u talk to your doctor about this :
ADVAIR contains salmeterol. In patients with asthma, medicines like salmeterol may increase the chance of asthma-related death. So ADVAIR is not for people whose asthma is well controlled on another controller medicine.
(4.) If so what did he or she say about it???
I’m afraid to take it because of that but my doctor really wants me to.I wasn’t tested for asthma but I took prednoise pills for it & it helped so my doctor said thats what I have.
(5.) Did u get a test done to see if u had asthma???
(6.) What are ALL your asthma symptoms???
(7.) What inhaler do u use for asthma???
Please reply soon.
Thanks
A: 1, 2. Yes, I am on the pill Singulair. I know I was on some kind of steroid inhaler before, but the name escapes me.
3, 4 Yes, and technically I shouldn’t answer this question because I *used to* be on Advair. It didn’t do much for me, and because of the hypothetical risks, and cost, we dropped it. My Brother The Doctor (family practice) only recommends Advair if other stuff doesn’t work.
5. There is no real test for asthma. If someone has the symptoms, you treat it like asthma, if you get better, Bingo!
6. Shortness of breath and wheezing, usually induced by: (a) exercise and (b) certain allergies (dust, pollen, something blooming every spring).
It can progress to a persistent (like for months) cough, when that gets bad I can’t sleep at night unless propped up.
The symptoms get worse when I lie down, better with warm, moist air.
Since I monitor myself, I’ve never had to have a full fledged attack, where I couldn’t breath and have to get taken to the hospital.
7. I have Albuterol for treating the symptoms/when things get bad. I take Singular daily as prevention. As a side note, I also drink lots of water when I am symptomatic. It seems to help loosen things up in my chest.
Also – my pulmonologist said to avoid cough suppressants whenever possible. He said they just make it harder to get the stuff out of your lungs (my simplification). I do take expectorant when I’m coughing, it does help.
There is a lot of information on how to live well with your asthma, the National Institute of Health link below could be a good starting point.
Q: Mr. Usher takes the following regimen for his asthma?
Advair 250/50 1 puff bid. what should Mr. Usher do after taking his dose of Advair? how much fluticasone and salmeterol would Mr. Usher receive in 1 month? which 2 brand name drugs does Advair Diskus replace?
A: After taking his dose of Advair, he should be sure to rinse his mouth out, as Advair can cause thrush (a superficial infection of the skin and mucous membranes in the mouth). It is a yeast infection. It can cause inflammation and discomfort.
How much medication he receives in one month depends on the number of days that month: 56 inhalations in February (58 if it is a leap year), 30 inhalations in months with 30 days, and 62 inhalations during the 31 day months.
The two brand name medications the Advair Diskus replaces are Flovent and Serevent.
I hope this answer was helpful!
Q: Hayfever causing Asthma?
Hi, I suffer from hayfever which I can bear for the 2 or so early months of the yr I get it, however more concerning this yr is the onset of what feels like shortness of breath and lung capacity, more so when I exercise and sometimes at night. I’ve been prescribed a puffer Salmeterol to ‘prevent’ wheezing’.
Anyone any experieince of this and how to overcome the onset of this type of condition..main worry is the dibilitating effect of not being able to exercise freely without the shortness of breath ?
A: OK, first of all Salmeterol (or any LABA) should NEVER be prescribed on it’s own without a corticosteroid inhaler. It really sounds like your prescriber does not have current up to date information regarding prescribing.
It’s actually dangerous to prescribe Salmeterol without a corticosteroid. I suggest you see your Doctor again or ask to be referred to an Asthma specialist. If you have exercise induced Asthma and find your current management is not working, having a corticosteroid inhaler might do the trick. Singulair as an add on is very effective too, however 20% of people do not respond to Singulair.
Either way, your current management is in urgent need of reviewing.
Q: About Asthma ADVAIR DISKUS Medince?
(1.) What ALL does this mean:
Rarely,serious(sometimes fatal) asthma-related breathing problems have occurred with the use of long-acting inhaled beta agonists(e.g.,salmeterol)
(2.) Does that mean that u can have a really bad asthma attack using this medince where u will be making noise when your breathing & everyone willl know that your having a really bad asthma attack???
(3.) If that was going to happen after taking the medince when would it???
(4.) If someone was going to have worseing of breathing after taking a medince when would they???
(5.) How do u know if your having wroseing of breathing from a medice or an asthma attack???
Since having wrosening of breathing is an asthma attack???
Please Answer ALL 5 Questions.
Everyone!!!
A: 1) Salmeterol (Serevent) is not a rescue medication. Because it takes about a half hour to take effect, if you use Salmeterol for an asthma attack, it won’t work like an Albuterol inhaler would. When you’re having an asthma attack, never take Advair to treat it. Use your rescue inhaler. Inhaled steroid, like the Flovent in Advair, is also not a rescue medication.
2) What this means is that Salmeterol is not for use as a rescue medication. If someone was to use it like that, it might not work fast enough to do anything about an asthma attack. Therefore, taking Salmeterol for an asthma attack is almost as bad as doing nothing about it. Using your rescue inhaler is recommended.
3) If you took Advair to treat an asthma attack, you might not get relief from it.
4) Bronchodilators (like Serevent and Albuterol) do have a potential side effect of bronchoconstriction/bronchospasm. In my experience, I haven’t seen it happen yet. Sometimes a stronger bronchodilator might be needed, if Albuterol isn’t strong enough for rescue. Xopenex is often used in that situation. If you knew that your symptoms would worsen when using a medication, logically I would not use it. Getting a doctor’s appointment and asking about switching to something else is a good idea if that happens.
5) If you take your medication and nothing happens, that’s a good sign that your asthma is getting worse or your medication is losing effect (it happens rarely). Generally, I think that worsening of breathing and asthma attacks are similar enough to warrant the same treatment.
I was on Advair 500/50 for a few months. I found that it was safe and effective. One thing I noticed was that I had little spots of blood on tissues when I blew my nose. It was a bit weird, but actually is a side effect.
When taking an inhaled steroid, it’s extremely important to gargle/rinse your mouth after you take it, then spit the water out. I’ve seen some patients I treated swallow the water after rinsing and I did it too, for a short time. My stomach was upset by this. I don’t recommend swallowing the rinse water.
Not doing this can lead to thrust (fungus on your tongue) developing. It’s something that you can also combat by brushing your tongue and using mouth watch.
It sounds like you’ve been reading the product manuscript or the information form that came from your pharmacy. Good job! Informed patients are a good thing. What you need to understand about the information you were provided with is that severe side effects are rare or happen when the medication is not used properly. I would keep in mind what the side effects are, so that you will know if it’s related to what you’re experiencing.
An alternative to Advair is Symbicort. It comes in a variety of strengths, just as Advair does. The advantage to Symbicort is that it has been approved (in Canada and Europe, I don’t know about the US) for use as a rescue inhaler too. In effect, all you would be using is Symbicort. There have been studies showing that the Pulmicort (inhaled steroid) in Symbicort helps to reduce the severity of an asthma attack over time. This happens because, the patient takes their Symbicort for an asthma attack, then is fine. The dose of inhaled steroid they just took helps prevent further asthma attacks. I like the idea of it. I feel that Symbicort as a long-acting controller and as a rescue inhaler will revolutionize asthma treatment like Advair did when it came out. There is a possibility that asthmatics might only need one inhaler for all purposes. That’s a lot simpler than knowing how to use an Advair diskus and an Albuterol inhaler. Less patient education is then required for them to be able to use their devices properly. Advair is great though, too. I’m not discounting it at all. It just isn’t meant to be used during an asthma attack under any circumstances.
Q: ASVAIR DISKUS WARNING Means???
ADVAIR DISKUS WARNING Means???
Question Details: What ALL does this Advair Diskus Warning Mean???
Read this ALL please& Than Answer:
Rarely,serious(sometimes fatal) asthma-related breathing problems have occurred with the use of long-acting inhaled beta agonists(e.g.,salmeterol)… product contains salmeterol in combination with fluticasone(a corticosteriod)It is not known if adding corticosteriod changes this risk.Therefore patients with asthma,this drug should only be prescribed when one long-term medication(e.g. inhaled corticosteriods)does not control breathing problems or when more than one long- term medication is clearly needed to control breathing problems.Before using this medication, it is important to learn how to use it properly.Discuss the risks and benefits of treatment with this medication with your doctor.
What ALL does it mean???
I’m so worried about taking it :*( :*( :*(
A: Don’t worry about it. I have been taking that discus for almost 3 years now, twice a day, everyday. What it means is that there is a slight risk because it is a steroid, but it is quite safe. The only thing you do NEED to do is rinse your mouth out after using it, because the powder you inhale could cause thrush (a mouth infection). Don’t worry, it is great and has really helped my asthma a lot! Good luck to you!
Q: ADVAIR DISKUS WARNING Means???
ADVAIR DISKUS WARNING Means???
Question Details: What ALL does this Advair Diskus Warning Mean???
Read this ALL please& Than Answer:
Rarely,serious(sometimes fatal) asthma-related breathing problems have occurred with the use of long-acting inhaled beta agonists(e.g.,salmeterol)… product contains salmeterol in combination with fluticasone(a corticosteriod)It is not known if adding corticosteriod changes this risk.Therefore patients with asthma,this drug should only be prescribed when one long-term medication(e.g. inhaled corticosteriods)does not control breathing problems or when more than one long- term medication is clearly needed to control breathing problems.Before using this medication, it is important to learn how to use it properly.Discuss the risks and benefits of treatment with this medication with your doctor.
What ALL does it mean???
I’m so worried about taking it but I was prescribed it.
A: It basically means that not everyone can use this medication. Some people may have an allergic reaction to one of the ingrediants. Some people may find the drug does not help their asthma.
There are similar (or even more horrifying) warnings on every drug made.
What’s more important with advair (which I’ve taken for years) is that you shake it well, hold it level, breathe in, do NOT breathe out into the canister, and rinse your mouth afterwards.
Q: Please save me from acnes.?
i’m a 18yr old boy. they are all over my cheeks and my forehead. i have tried antiseptic lotions but they don’t really help. is there anyway of controlling them? btw i have asthma and hence have to take steroids daily(salmeterol and fluticasone combination) i also have a general allergic tendency and often take cetrizine and use only mild soaps (dove). are they responsible?
A: A friend of mine got a book about getting rid of acne a while back. He followed the infor in it and it cleared up the acne on his face, shoulders and back almost completely.
Heres their website: http://www.yourlifestyle.info/acnefree
Q: ADVAIR DISKUS Medince?
(1.) What ALL does this mean:
Rarely,serious(sometimes fatal) asthma-related breathing problems have occurred with the use of long-acting inhaled beta agonists(e.g.,salmeterol)
(2.) Does that mean that u can have a really bad asthma attack using this medince where u will be making noise when your breathing & everyone willl know that your having a really bad asthma attack???
(3.) If that was going to happen after taking the medince when would it???
(4.) If someone was going to have worseing of breathing after taking a medince when would they???
(5.) How do u know if your having wroseing of breathing from a medice or an asthma attack???
Since having wrosening of breathing is an asthma attack???
Please Answer ALL 5 Questions.
Everyone!!!
A: have taken advair and i have had no bad affects from this medicine i have asthma and i dn’t think there is nothing wrong with it.
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